Population pharmacokinetics of dolutegravir in HIV‐infected treatment‐naive patients

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Population pharmacokinetics of dolutegravir in HIV-infected treatment-naive patients

AIM Dolutegravir is the newest integrase inhibitor approved for HIV treatment and has demonstrated potent antiviral activity in patient populations with a broad range of treatment experience. This analysis aimed to characterize the population pharmacokinetics of dolutegravir in treatment-naive patients and to evaluate the influence of patient covariates. METHODS A population pharmacokinetic m...

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ژورنال

عنوان ژورنال: British Journal of Clinical Pharmacology

سال: 2015

ISSN: 0306-5251,1365-2125

DOI: 10.1111/bcp.12639